Key developments in molecular biology, bioinformatics and drug development have positioned Superfluid to leverage cf-mRNA to create accurate and clinically useful diagnostic tests.
Technology behind Superfluid
- Superfluid has developed new methods for characterizing highly complex, rare fragments of mRNA in blood
- Evolution of knowledge around pathways and novel computational techniques for processing and interpreting big data sets has enabled the formation of the Superfluid proprietary database
- Proliferation of expensive and highly effective targeted therapeutics has created an urgent need for diagnostics to facilitate informed selection
Sequencing and qPCR
Tissue specific gene expression database
Algorithm development by machine learning
Deconvolution of disease state
Koh W, et al. (2014)
Noninvasive in vivo monitoring of tissue-specific global gene expression in humans. PNAS 111(20):7361–7366.
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Cell types of origin of the cell-free transcriptome. Nat Biotechnol. Jun;40(6):855-861.
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